The Siloli is a desert in southwestern Bolivia, located in the department of Potosi. Administratively, it is located within the municipality of San Pablo de Lípez in the province of Sud Lípez. It is characterized by its rocky formations as a result of the strong winds in the region. The desert is considered one of the driest in the world1 due to the low rainfall in the area. It is usually part of tourist routes, as it is the gateway to the National Reserve of Andean Fauna Eduardo Abaroa and its surroundings are the colored lagoons and the Gran Salar de Uyuni. It is located at an average altitude of 4500 meters above sea level.

It is considered part of the Atacama Desert, the driest desert in the world.